Cryptic crossword clue
Laboratory turning to American business an ornamental railing

The most common and most likely answer to this crossword clue is the 10 letter word BALUSTRADE

I've seen this crossword clue in The Guardian
B
A
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Buddy explains!

The straight part
We know that "ornamental railing" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case ornamental railing = balustrade.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does BALUSTRADE mean?

BALUSTRADE noun
  1. A row of balusters topped by a rail, serving as an open parapet, as along the edge of a balcony, terrace, bridge, staircase, or the eaves of a building.

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