The most common and most likely answer to this crossword clue is the 6 letter word APNOEA
I've seen this crossword clue in Financial Times
A
P
N
O
E
A
More clues leading to the result APNOEA
- Issue of sleeping adults involving open chops
- Problem sleeping? One surprisingly found in alpha male relative
- Chap – no earplugs – part of the problem in sleeping?
- Lack of breath an ape suffers when without oxygen
- Happen to be sad, every so often, where one temporarily stops breathing
- Chimpanzee gets no first aid during breathing difficulty
- . Drunken peon surrounded by inveterate drinkers gets breathing problem
- Breathing problem of former tipplers ingesting open cocktail
- Refuse to stop copy — a complaint
- Breathlessness due to open conflict in support group
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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.