Cryptic crossword clue
Lack of interest concerning argument 12

The most common and most likely answer to this crossword clue is the 12 letter word INDIFFERENCE

I've seen this crossword clue in The Times
I
N
D
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F
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The straight part
We know that "Lack of interest" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case lack of interest = indifference.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

Crossword Answer definitions

INDIFFERENCE noun
  1. The state of being indifferent.
  2. Unbiased impartiality.
  3. Unemotional apathy.
  4. A lack of enthusiasm.
  5. Unconcerned nonchalance.

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