The most common and most likely answer to this crossword clue is the 9 letter word AMORALITY
I've seen this crossword clue in The Guardian
A
M
O
R
A
L
I
T
Y
More clues leading to the result AMORALITY
- Lack of principles said to obstruct friendship
- Unprincipled position spoken in friendship
- Position that’s not ethical in test breaking up friendship
- Lack of certain standards in test getting in the way of friendly relations
- Spoken in friendship, it's not about what's right or wrong
- Girl takes test — it doesn't say right or wrong
- Unwritten test going into friendship’s lack of ethics
Buddy explains!

The straight part
We know that "Lack of principles" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case lack of principles = amorality.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.