The most common and most likely answer to this crossword clue is the 7 letter word BOREDOM
I've seen this crossword clue in The Sunday Telegraph
B
O
R
E
D
O
M
More clues leading to the result BOREDOM
- Report framing left-winger’s apathy
- Way to screw up irksome state
- Lack of interest in wine in time of prosperity
- Soldiers in base recalled Missouri as “state of no interest“
- Pole’s signal to stop breaking monotony
- Did nurse prepare Mark for weariness?
- Lack of interest in way mug flipped over
- Glowing report’s outstanding monotony
- Mental state induced by bedroom shenanigans?
- Tolerated party finale in glum tedium
Buddy explains!

The straight part
We know that "Lack of satisfaction" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case lack of satisfaction = boredom.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does BOREDOM mean?
BOREDOM noun- The state of being bored.
- An instance or period of being bored; A bored state.