Cryptic crossword clue
Lacking energy, Fred’s friend’s unsympathetic when heading off for area of US farm 8

The most common and most likely answer to this crossword clue is the 8 letter word BARNYARD

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Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does BARNYARD mean?

BARNYARD noun
  1. The yard associated with or surrounding a barn.

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