The most common and most likely answer to this crossword clue is the 6 letter word FEEBLE
I've seen this crossword clue in Independent
F
E
E
B
L
E
More clues leading to the result FEEBLE
- Unconvincing feel about opening of bowling, English
- The Spanish moan, upset and weak
- Weak grouse sent skyward ends in trivial chase
- Weak insect caught by mischievous child jumping up
- Pathetic complaint backed by the Parisian
- Foolish complaint about the French heeded
- Pathetic complaint upset the French
- Complain about love when heartless and impotent
- Lame cattle put up on sale — just 50%?
- Feel and be stimulated, then faint
Buddy explains!

The straight part
We know that "lame" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case lame = feeble.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does FEEBLE mean?
FEEBLE verb- To make feeble; to enfeeble.
- Deficient in physical strength
- Lacking force, vigor, or efficiency in action or expression; faint.