The most common and most likely answer to this crossword clue is the 8 letter word HOBBLING
I've seen this crossword clue in Financial Times
H
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More clues leading to the result HOBBLING
Buddy explains!

The straight part
We know that "Lame" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case lame = hobbling.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
Crossword Answer definitions
HOBBLING verb- To fetter by tying the legs; to restrict (a horse) with hobbles.
- To walk lame, or unevenly.
- To move roughly or irregularly.
- To perplex; to embarrass.
- The movement of one who hobbles.