The most common and most likely answer to this crossword clue is the 6 letter word HUDSON
I've seen this crossword clue in The Daily Telegraph
H
U
D
S
O
N
More clues leading to the result HUDSON
- Rock in river?
- Rock in river
- Hound story’s beginning altered for American banker
- Honour received by old German explorer
- Landlady in ‘Hound’ novel accommodating Sherlock, principally
- With temperature dropping, knock boy in river
- Running hounds bay in Canada?
- . Hounds ran away to river
- Rock flower
- Marine explorer heads for home upsetting daughter and her brother?
Buddy explains!
The straight part
We know that "Landlady" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case landlady = hudson.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.