The most common and most likely answer to this crossword clue is the 7 letter word SHIELDS
I've seen this crossword clue in The Guardian
S
H
I
E
L
D
S
Buddy explains!

The straight part
We know that "guards" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case guards = shields.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does SHIELDS mean?
SHIELDS noun- Anything that protects or defends; defense; shelter; protection.
- A shape like that of a shield; usually, an inverted triangle with sides that curve inward to form a pointed bottom, commonly used for police identifications and company logos.
- A large expanse of exposed stable Precambrian rock.
- A place with a toilet seat: an outhouse; a lavatory.
- Parts at the front and back of a vehicle which are meant to absorb the impact of a collision
- To protect, to defend.
- To protect from the influence of