The most common and most likely answer to this crossword clue is the 4 letter word SLAB
S
L
A
B
More clues leading to the result SLAB
- Turning thin wood mostly is a piece of cake
- Small dog’s large slice of cake
- Block, playing back what are bowled short of a length
- Getting thin wood cut up is a piece of cake, perhaps
- Small sailor pursuing large hunk
- Substantial piece of cake, second, shortened party
- Hunk‘s small short dog
- Block within this laboratory
- Large part of small science room
Buddy explains!

The straight part
We know that "Large part" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case large part = slab.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does SLAB mean?
SLAB noun- A large, flat piece of solid material; a solid object that is large and flat.
- A paving stone; a flagstone.
- A carton containing 24 cans of beer.
- An outside piece taken from a log or timber when sawing it into boards, planks, etc.
- A bird, the wryneck.
- The slack part of a sail.
- A large, luxury pre-1980 General Motors vehicle, particularly a Buick, Oldsmobile or Cadillac.
- A very large wave.
- A sequence of 12 adjacent bits, serving as a byte in some computers.
- Part of a tectonic plate that is being subducted.
- To make something into a slab.
- Mud, sludge.
- Thick; viscous.
- A car that has been modified with equipment such as loudspeakers, lights, special paint, hydraulics, and other accessories.