Cryptic crossword clue
Last car of the train contains a large can 9

The most common and most likely answer to this crossword clue is the 9 letter word CALABOOSE

C
A
L
A
B
O
O
S
E

Buddy explains!

The straight part
We know that "can" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case can = calaboose.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CALABOOSE mean?

CALABOOSE noun
  1. A prison or jail/gaol.

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