The most common and most likely answer to this crossword clue is the 6 letter word GALWAY
I've seen this crossword clue in The Daily Telegraph
G
A
L
W
A
Y
More clues leading to the result GALWAY
- Irish port -- girl needs route
- Golf ever mostly in Irish location
- County is grand nearly the whole time
- Trail leading away from street in Irish port
- Girl on track in Irish city
- West coast county supporting government almost every time
- See: not in SW Scotland, found in Ireland
- City finding goalscorer’s head almost every time
- Look away from cattle, James?
- Go astray and delay returning to Irish port
Buddy explains!
The straight part
We know that "port city" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case port city = galway.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.