Cryptic crossword clue
   Lead scientific study, maybe touched by extremely awful disease 10

The most common and most likely answer to this crossword clue is the 10 letter word METALLURGY

I've seen this crossword clue in Independent
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Buddy explains!

The straight part
We know that "Lead scientific study, maybe" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case lead scientific study, maybe = metallurgy.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does METALLURGY mean?

METALLURGY noun
  1. The science of metals; their extraction from ores, purification and alloying, heat treatment, and working.

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