Cryptic crossword clue
Leader of thieves is out of time holding up miners, resisting attacks 6

The most common and most likely answer to this crossword clue is the 6 letter word IMMUNE

I've seen this crossword clue in The Guardian
I
M
M
U
N
E


Buddy explains!

The straight part
We know that "resisting attacks /resisting attacks" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case resisting attacks /resisting attacks = immune.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does IMMUNE mean?

IMMUNE noun
  1. A person who is not susceptible to infection by a particular disease
IMMUNE verb
  1. To make immune.
IMMUNE adjective
  1. (usually with "from") Exempt; not subject to.
  2. (usually with "to") Protected by inoculation, or due to innate resistance to pathogens.
  3. (by extension) Not vulnerable.
  4. Of or pertaining to the immune system.

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