Cryptic crossword clue
Leading man I suspect, about which a word of caution? 8

The most common and most likely answer to this crossword clue is the 8 letter word DOMINANT

I've seen this crossword clue in The Guardian
D
O
M
I
N
A
N
T


Buddy explains!

The straight part
We know that "Leading" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case leading = dominant.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DOMINANT mean?

DOMINANT noun
  1. The fifth major tone of a musical scale (five major steps above the note in question); thus G is the dominant of C, A of D, and so on.
  2. The triad built on the dominant tone.
  3. A gene that is dominant.
  4. A species or organism that is dominant.
  5. (BDSM) The dominating partner in sadomasochistic sexual activity.
DOMINANT adjective
  1. Ruling; governing; prevailing
  2. Predominant, common, prevalent, of greatest importance.
  3. Designating the follicle which will survive atresia and permit ovulation.

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