The most common and most likely answer to this crossword clue is the 2 plus 6 letter word UP STICKS
U
P
S
T
I
C
K
S
More clues leading to the result UP STICKS
- Make off before the judge stands
- Move staff in periods of good fortune.
- Move or don’t move in periods of prosperity?
- Move on horseback, approaching hurdles
- Remove clogs, seeing good time ahead
- Move to London maybe and stay with son
- Good times, good marks? Get away!
- Californian rises with sun in shift
- Stay during good times then leave abruptly
- Leave problem with one of computer’s arrow keys?
Buddy explains!

The straight part
We know that "Leave" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case leave = up sticks.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.