Cryptic crossword clue
Left in agony, went into decline 10

The most common and most likely answer to this crossword clue is the 10 letter word LANGUISHED

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "went into decline" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case went into decline = languished.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does LANGUISHED mean?

LANGUISHED verb
  1. To lose strength and become weak; to be in a state of weakness or sickness.
  2. To pine away in longing for something; to have low spirits, especially from lovesickness.
  3. To live in miserable or disheartening conditions.
  4. To be neglected; to make little progress, be unsuccessful.
  5. To make weak; to weaken, devastate.
  6. To affect a languid air, especially disingenuously.

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