The most common and most likely answer to this crossword clue is the 8 letter word SOUTHPAW
S
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A
W
More clues leading to the result SOUTHPAW
- Boxer beaten up, so what!
- Boxer understood about available payment method
- Boxer who sat up, befuddled
- What’s up, old battered fighter?
- What’s up high, punched by old boxer?
- Fighter who’s put out about amateur
- Boxer getting up to wash potty
- Lefty messed up — so what?
- What’s up, possibly, outside ring for unusual boxer
- Unorthodox fighter in corrupt ring. What’s up?
Buddy explains!

The straight part
We know that "Lefty" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case lefty = southpaw.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does SOUTHPAW mean?
SOUTHPAW noun- One who is left-handed, especially in sports.
- A boxer who leads with the right hand and guards with the left