The most common and most likely answer to this crossword clue is the 6 letter word UMBRIA
I've seen this crossword clue in The Sunday Telegraph
U
M
B
R
I
A
More clues leading to the result UMBRIA
- Leader leaves English county for Italian region
- Barium processed in Italian region
- Italian region that tops the Lake District
- Classy medic and artist tour Italy, or part of it
- Part of England not cold? It’s part of Italy
- Mountainous region abroad? You’ll find England’s hilly area less cold
- Region of county that’s less cloudy
- Let me see rose cut in Italian region
- Caught leaving English county for a mountainous region of Italy
- Head off from English county to see Italian region
Buddy explains!
The straight part
We know that "Italian region" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case italian region = umbria.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.