The most common and most likely answer to this crossword clue is the 7 letter word VAMOOSE
I've seen this crossword clue in The Sunday Telegraph
V
A
M
O
O
S
E
More clues leading to the result VAMOOSE
- Escape with a move so disorderly?
- Leave Virginia with American deer
- Take flight that’s sound from Jersey, boarding vessel
- Let’s go low boarding vessel
- Elk to the south of Virginia leave in a hurry
- Go low to puncture vessel
- See a large elk get lost!
- Take flight, low, aboard vessel
- Leave Virginia with American beast
- Go low inside vessel
Buddy explains!

The straight part
We know that "Let’s go" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case let’s go = vamoose.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does VAMOOSE mean?
VAMOOSE verb- To run away (from); to flee.
- To hurry.
- To be expelled.