The most common and most likely answer to this crossword clue is the 5 letter word THETA
I've seen this crossword clue in The Times
T
H
E
T
A
More clues leading to the result THETA
- Times covering that man, a Greek character
- Letter and article presented with show of gratitude
- Letter has half of them worried in recession
- Greek character the volunteers wanted here
- Woman digesting opening of tough letter from abroad
- Article gets thank you letter
- Character in Greek article volunteers
- … and article cheers one of its characters
- Letter of thanks after article
- Article cheers Greek character
Buddy explains!

The straight part
We know that "Letter" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case letter = theta.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does THETA mean?
THETA noun- The eighth letter of the Modern Greek alphabet, ninth in Old Greek: Θ, θ.
- The measure of an angle.
- The sensitivity of the value of a derivative with respect to time; the "time decay".
- Designating a level of brain activity as measured by electroencephalography having a frequency of between four and seven cycles per second (associated with drowsiness in adults).
- The voiceless dental fricative represented by θ.