Cryptic crossword clue
Letters from abroad: at least twenty two? 3

The most common and most likely answer to this crossword clue is the 3 letter word XIS

I've seen this crossword clue in The Times
X
I
S

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The straight part
We know that "Letters from abroad" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case letters from abroad = xis.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does XIS mean?

XIS noun
  1. The 14th letter of Classical and Modern Greek. The 15th in Ancient and Old Greek.
  2. Either of a pair of hyperons having spin 1/2, which decay into a lambda particle and a pion.

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