Cryptic crossword clue
Like lions, affected outside protected area, finally 10

The most common and most likely answer to this crossword clue is the 10 letter word PREDACIOUS

I've seen this crossword clue in The Sunday Telegraph
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The straight part
We know that "Like lions" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case like lions = predacious.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does PREDACIOUS mean?

PREDACIOUS adjective
  1. Surviving by preying on other animals.

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