Cryptic crossword clue
Like one separating people making spiteful remarks 10

The most common and most likely answer to this crossword clue is the 10 letter word ASPERSIONS

I've seen this crossword clue in The Times
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The straight part
We know that "spiteful remarks" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case spiteful remarks = aspersions.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ASPERSIONS mean?

ASPERSIONS noun
  1. An attack on somebody's reputation or good name, often in the phrase to cast aspersions upon….
  2. A sprinkling, especially of holy water.
  3. (in plural) slander, calumny

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