Cryptic crossword clue
Like simple life in college, until having to be evacuated into vault 11

The most common and most likely answer to this crossword clue is the 11 letter word UNICELLULAR

I've seen this crossword clue in The Times
U
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L
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The straight part
We know that "Like simple life" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case like simple life = unicellular.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does UNICELLULAR mean?

UNICELLULAR noun
  1. A single-celled organism; a unicell.
UNICELLULAR adjective
  1. Describing any microorganism that has a single cell

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