Cryptic crossword clue
Like snakes, four having shed skin inside hole 7

The most common and most likely answer to this crossword clue is the 7 letter word SINUOUS

I've seen this crossword clue in The Sunday Telegraph
S
I
N
U
O
U
S

Buddy explains!

The straight part
We know that "Like snakes" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case like snakes = sinuous.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SINUOUS mean?

SINUOUS adjective
  1. Having curves in alternate directions; meandering.
  2. Moving gracefully and in a supple manner.
  3. Morally crooked; shifty.

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