Cryptic crossword clue
Like spreadsheet, perhaps, when requiring a fresh start 6,4

The most common and most likely answer to this crossword clue is the 6 plus 4 letter word TABULA RASA

I've seen this crossword clue in Independent
T
A
B
U
L
A
R
A
S
A

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

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