The most common and most likely answer to this crossword clue is the 3 letter word EFT
I've seen this crossword clue in The Times
E
F
T
More clues leading to the result EFT
- Amphibian originally eaten for tea
- Decapitated nimble little creature
- Aquatic amphibian moved away, missing lake
- Little creature went without starter
- Once again alien force invades
- Port gets rid of large amphibian
- Being terrestrial, force captured by extra-terrestrial
- Small creature takes Echo – newspaper we prefer!
- Duke dispatched by clever, cold-blooded creature
- Small creature, one airbrushed from electronic picture
Buddy explains!

The straight part
We know that "Little creature" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case little creature = eft.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does EFT mean?
EFT noun- A newt, especially the European smooth newt (Lissotriton vulgaris, syn. Triturus punctatus).
- Again; afterwards