Cryptic crossword clue
Little creatures in trunk road restricting vehicle 5

The most common and most likely answer to this crossword clue is the 5 letter word ACARI

A
C
A
R
I

Buddy explains!

The straight part
We know that "Little creatures" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case little creatures = acari.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ACARI mean?

ACARI noun
  1. (acarology) Any member of the subclass Acari (aka Acarina): thus, a mite or a tick; specifically, any mite of the genus Acarus.

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