The most common and most likely answer to this crossword clue is the 4 letter word MINI
I've seen this crossword clue in The Times
M
I
N
I
More clues leading to the result MINI
- A mouse is heard in vehicle
- Little car entering Jerusalem in Israel
- Note short skirt
- Game ending in hullabaloo, filming abandoned
- Little friend of Mickey being heard
- Mother’s taken off least skimpy garment
- Car in showroom in Islington
- I'm moving backwards in reversing car
- Piece of trim in Italian car
- It’s briefly worn by female in dorm, initially
Buddy explains!

The straight part
We know that "Little" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case little = mini.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does MINI mean?
MINI adjective- Miniature, tiny, small.
- A miniskirt.
- A minicomputer.