Cryptic crossword clue
Lives away from one’s house with Rex and four flipping good players 8

The most common and most likely answer to this crossword clue is the 8 letter word VIRTUOSI

I've seen this crossword clue in The Guardian
V
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T
U
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I


Buddy explains!

The straight part
We know that "good players" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case good players = virtuosi.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does VIRTUOSI mean?

VIRTUOSI noun
  1. An expert in virtù or art objects and antiquities; a connoisseur.
  2. Someone with special skill or knowledge; an expert.
  3. Specifically, a musician (or other performer) with masterly ability, technique, or personal style.

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