The most common and most likely answer to this crossword clue is the 6 letter word AGAMAS
A
G
A
M
A
S
Buddy explains!
The straight part
We know that "Lizards" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case lizards = agamas.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does AGAMAS mean?
AGAMAS noun- Any of the various small, long-tailed lizards of the subfamily Agaminae of family Agamidae, especially in genera Acanthocercus, Agama, Dendragama, Laudakia, Phrynocephalus, Trapelus and Xenagama.