The most common and most likely answer to this crossword clue is the 6 letter word ABHORS
I've seen this crossword clue in The Guardian
A
B
H
O
R
S
More clues leading to the result ABHORS
Buddy explains!
The straight part
We know that "Loathes/Loathes" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case loathes/loathes = abhors.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does ABHORS mean?
ABHORS verb- To regard with horror or detestation; to shrink back with shuddering from; to feel excessive repugnance toward; to detest to extremity; to loathe.
- To fill with horror or disgust.
- To turn aside or avoid; to keep away from; to reject.
- (canon law) To protest against; to reject solemnly.
- To shrink back with horror, disgust, or dislike; to be contrary or averse; construed with from.
- Differ entirely from.