The most common and most likely answer to this crossword clue is the 9 letter word LIDOCAINE
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More clues leading to the result LIDOCAINE
Buddy explains!
The straight part
We know that "Local" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case local = lidocaine.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does LIDOCAINE mean?
LIDOCAINE noun- A local anesthetic [2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide], that is also used as a antiarrhythmic drug.