Cryptic crossword clue
Lock up in box, care taken moving around inside 11

The most common and most likely answer to this crossword clue is the 11 letter word INCARCERATE

I've seen this crossword clue in Financial Times
I
N
C
A
R
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Buddy explains!

The straight part
We know that "Lock up" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case lock up = incarcerate.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does INCARCERATE mean?

INCARCERATE verb
  1. To lock away; to imprison, especially for breaking the law.
  2. To confine; to shut up or enclose; to hem in.

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