Cryptic crossword clue
Lock up in packing case taking unusual care

The most common and most likely answer to this crossword clue is the 11 letter word INCARCERATE

I've seen this crossword clue in Independent
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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does INCARCERATE mean?

INCARCERATE verb
  1. To lock away; to imprison, especially for breaking the law.
  2. To confine; to shut up or enclose; to hem in.

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