Cryptic crossword clue
London, for example, wins one away from Uber — it reduces profits 7,5,3

The most common and most likely answer to this crossword clue is the 7 plus 5 plus 3 letter word CAPITAL GAINS TAX

I've seen this crossword clue in The Guardian
C
A
P
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T
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L
G
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T
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X

Buddy explains!

The straight part
We know that "it reduces profits" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case it reduces profits = capital gains tax.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

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