The most common and most likely answer to this crossword clue is the 3 plus 4 letter word BIG TIME
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More clues leading to the result BIG TIME
Buddy explains!

The straight part
We know that "at the top of eg show business" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case at the top of eg show business = big time.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does BIG TIME mean?
BIG TIME adjective- Of major significance or importance.
- To a significant degree.