Cryptic crossword clue
Loo permits distributed in big city 10

The most common and most likely answer to this crossword clue is the 10 letter word METROPOLIS

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The cryptic/wordplay part
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This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does METROPOLIS mean?

METROPOLIS noun
  1. (history) The mother (founding) polis (city state) of a colony.
  2. A large, busy city, especially as the main city in an area or country or as distinguished from surrounding rural areas.
  3. (canon law) The see of a metropolitan archbishop, ranking above its suffragan diocesan bishops.
  4. A generic focus in the distribution of plants or animals.

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