The most common and most likely answer to this crossword clue is the 4 letter word LOBE
I've seen this crossword clue in The Guardian
L
O
B
E
More clues leading to the result LOBE
- Cerebral part lost on British electorate originally
- See live part of brain
- Look at live part of organ
- Left order for portion of liver
- Projection bringing learner royal recognition
- Order will come after leader’s first rounded projection
- Globetrotter spilling gin-and-tonic — bounder! — where studs hang out
- Liberal award for division
- Throw earth round part of ear
- Hearing part of high-pitch note
Buddy explains!

The straight part
We know that "part of organ" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case part of organ = lobe.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does LOBE mean?
LOBE noun- Any projection or division, especially one of a somewhat rounded form.
- A clear division of an organ that can be determined at the gross anatomy level, especially one of the parts of the brain, liver or lung.
- A semicircular pattern left on the ice as the skater travels across it.