Cryptic crossword clue
Loosen tie with nun having no initial sections from the East 7

The most common and most likely answer to this crossword clue is the 7 letter word UNSTRAP

U
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Buddy explains!

The straight part
We know that "Loosen tie" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case loosen tie = unstrap.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does UNSTRAP mean?

UNSTRAP verb
  1. To loosen or remove the straps from (something).

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