The most common and most likely answer to this crossword clue is the 5 letter word SCION
I've seen this crossword clue in Financial Times
S
C
I
O
N
More clues leading to the result SCION
- Descendant touring Channel Islands finding another one
- Descendant in India gatecrashing small party
- Twig, at last, Times Cryptic Number One’s being recalled
- Male of family that's kept in charge, after upsetting heir
- Start of scene with prisoner outside I shoot
- Sickie regularly taken by working offspring
- Relative embracing sources of child’s immunisation for young member of the family
- Shoot a young family member that’s forged coins
- Child care originally introduced in Israel
- Loses heart with civic leaders over issue
Buddy explains!

The straight part
We know that "issue" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case issue = scion.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does SCION mean?
SCION noun- A descendant, especially a first-generation descendant of a distinguished family.
- The heir to a throne.
- A guardian.
- A detached shoot or twig containing buds from a woody plant, used in grafting; a shoot or twig in a general sense.