Cryptic crossword clue
Losing cohesion is trickily disorientating 14

The most common and most likely answer to this crossword clue is the 14 letter word DISINTEGRATION

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Buddy explains!

The straight part
We know that "Losing cohesion" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case losing cohesion = disintegration.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DISINTEGRATION mean?

DISINTEGRATION noun
  1. A process by which anything disintegrates.
  2. The condition of anything which has disintegrated.
  3. A wearing away or falling to pieces of rocks or strata, produced by atmospheric action, frost, ice, etc.

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