Cryptic crossword clue
Lots of secreted stuff former girlfriends take out heartily 8

The most common and most likely answer to this crossword clue is the 8 letter word EXUDATES

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
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What does EXUDATES mean?

EXUDATES noun
  1. A fluid that has exuded from somewhere; especially one that has exuded from a pore of an animal or plant.

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