Cryptic crossword clue
Lots talking about Bach sextet – or something else 12

The most common and most likely answer to this crossword clue is the 12 letter word CHATTERBOXES

I've seen this crossword clue in Financial Times
C
H
A
T
T
E
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B
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S

Buddy explains!

The straight part
We know that "Lots talking" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case lots talking = chatterboxes.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CHATTERBOXES mean?

CHATTERBOXES noun
  1. An artificial intelligence program intended to simulate interactive conversation with another person
CHATTERBOXES noun
  1. One who chats or talks to excess.
  2. A cootie catcher (children's fortune-telling device).

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