The most common and most likely answer to this crossword clue is the 6 letter word RHEUMY
I've seen this crossword clue in The Times
R
H
E
U
M
Y
More clues leading to the result RHEUMY
- Unhealthy male in grip of unusual malady at last
- Suffering around the eyes, but uncongested, we’re told
- Spacious, from what we hear, but cold
- Loveless, your home turned cold and damp
- Damp and unhealthy, but spacious, we hear
- Persian poet sounds affected by cold
- It’s said capacious hanky’s needed, if you’re like this
- European overwhelmed by noise in railway with congestion
- It’s described as spacious but it’s unhealthily damp
- Having nasal problems allegedly, with plenty of space
Buddy explains!

The straight part
We know that "cold and damp" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case cold and damp = rheumy.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does RHEUMY mean?
RHEUMY adjective- Of, relating to, or producing rheum from the mucous membranes; watery