Cryptic crossword clue
Low-down run taking victory over a run 6

The most common and most likely answer to this crossword clue is the 6 letter word SCURVY

S
C
U
R
V
Y

Buddy explains!

The straight part
We know that "Low-down" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case low-down = scurvy.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SCURVY mean?

SCURVY noun
  1. A disease caused by insufficient intake of vitamin C leading to the formation of livid spots on the skin, spongy gums, loosening of the teeth and bleeding into the skin and from almost all mucous membranes.
SCURVY adjective
  1. Covered or affected with scurf or scabs; scabby; scurfy; specifically, diseased with the scurvy.
  2. Contemptible, despicable, low, disgustingly mean.

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