The most common and most likely answer to this crossword clue is the 8 letter word DISPIRIT
I've seen this crossword clue in The Daily Telegraph
D
I
S
P
I
R
I
T
More clues leading to the result DISPIRIT
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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does DISPIRIT mean?
DISPIRIT verb- To lower the morale of; to make despondent; to dishearten.