Cryptic crossword clue
Lower part of leg, middle part of leg and large bottom 5

The most common and most likely answer to this crossword clue is the 5 letter word KNEEL

K
N
E
E
L


Buddy explains!

The straight part
We know that "Lower part of leg" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case lower part of leg = kneel.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does KNEEL mean?

KNEEL verb
  1. To rest on one's bent knees, sometimes only one; to move to such a position.
  2. To cause to kneel.
  3. To rest on (one's) knees

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